The CRMSimulator is an easy-to-use implementation of the CRM
dose-finding method of Quigley, Pepe, and Fisher. The emphasis of this version
is simplicity, not generality; many features of previous versions which were
not commonly used have been removed. This software provides a simple setting in
which to experiment with adaptive dose-finding. A more general command line
implementation of the CRM is available
in finding an effective dose and not just a moderately toxic dose may be
interested in the
EffTox dose-finding method.
See also the
CRM method description
and CRMSimulator user's guide
available here and also included with the software.
Clift Norris developed the user interface using
and the Microsoft .NET framework version 1.1.
John Cook implemented the simulation kernel using Visual C++.