Last Modified Date | Product Name | Brief Description | |

2015-02-12 |
| Beta Binomial Distribution Demo | A learning tool to demonstrate a beta-binomial distribution prior being updated to become a posterior distribution |

2015-02-12 |
| Optimal Interval Design | An Optimal Bayesian phase I clinical trial design for finding the maximum tolerated dose (MTD) |

2015-01-30 |
| BMA CRM | Dose-finding software using the Bayesian Model Averaging Continual Reassessment Method, including Data Augmentation |

2014-08-27 |
| Pinnacle | A method for detection and quantification of protein spots from 2-D gel electrophoresis images. |

2014-05-22 |
| EffTox | Phase I/II dose-finding based on efficacy and toxicity |

2014-04-01 |
| Predictive Probabilities | Predictive probability interim analysis of clinical trials |

2013-11-26 |
| Inequality Calculator | Calculate the probability of one random variable being larger than another |

2013-11-22 |
| ParameterSolver | Solve for distribution parameters for common distributions |

2013-07-25 |
| Multc Lean | Monitoring toxicity and efficacy in phase II clinical trials |

2013-01-09 |
| Bayes Factor Binary | A Bayesian hypothesis test-based method for clinical trials with single arm binary patient outcomes |

2012-12-11 |
| TTEDesigner | Software for designing single arm safety monitoring trials with time-to-event endpoints |

2012-11-07 |
| UAROET | Phase I/II dose-finding with utility-based adaptive randomization and ordinal efficacy and toxicity. |

2012-10-05 |
| Toxicity Probability Intervals | Dose-finding based on toxicity probability intervals |

2012-06-06 |
| BlockARAND | Block adaptive randomization |

2012-05-25 |
| Bayes Factor TTE | Monitor single-arm time-to-event trials using Bayes factors |

2012-05-10 |
| WFMM | Wavelet-based functional mixed model software |

2012-05-03 |
| Multc99 | Monitoring multiple outcomes in clinical trials |

2012-04-19 |
| TTEConduct | Tabulate stopping conditions for single-arm time-to-event safety monitoring |

2011-12-02 |
| CONFINT | Calculates requisite sample size to achieve a specified probability of a confidence interval of at most a specified size. |

2011-12-02 |
| EXTSIG | Exact p-values for 2 by 2 tables |

2011-12-02 |
| SEQBIN | Bayesian/frequentist designs for sequential/group-sequential trials of a single binomial parameter |

2011-10-26 |
| Adaptive Randomization | Outcome-adaptive randomization for clinical trials |

2011-01-12 |
| Misclib | A collection of Fortran routines used in writing statistical software. |

2010-10-22 |
| STPLAN | Double-precision study planning calculations |

2010-10-15 |
| Parallel phase I and II design | C and C++ code for simultaneously evaluating efficacy and toxicities using a seamless phase I/II design for clinical trials of combination therapies. |

2010-10-15 |
| Phase II Predictive Probability | Computes the stopping boundaries for the predictive probability design of a single-arm Phase II study with a binary endpoint. |

2010-10-06 |
| CiBolus | Software for Optimizing the Concentration and Bolus of a Drug Delivered by Continuous Infusion |

2010-05-28 |
| SYNERGY | Determines the interaction of two drugs as synergy, additivity, or antagonism |

2009-11-11 |
| Response and Survival | Software associated with an adaptive randomization method using short-term and long-term response. |

2009-08-12 |
| ESS Regresssion | R software for computing the prior effective sample size of a Bayesian normal linear or logistic regession model |

2009-02-19 |
| Proportional density | Estimation and inference under semiparametric proportional density model |

2009-02-10 |
| U2OET | Phase I/II dose-pair-finding based on utilities of 3-level ordinal efficacy and toxicity. |

2009-01-06 |
| Dose Schedule Finder | Design and conduct Phase I clinical trials that simultaneously optimizes dose and schedule. |

2008-08-18 |
| CI of Interaction Index | Estimate interaction indices and their confidence intervals for assessing multiple drug interactions |

2008-05-08 |
| BP1CI | Computes Clopper-Pearson confidence intervals for one-sample binomial and Poisson |

2007-04-03 |
| PRT | Monitors late-onset toxicities in Phase I trials using predicted risks |

2007-04-02 |
| ANOVA DDP | Software for the ANOVA DDP model of De Iorio, Mueller, Rosner, and MacEachern. |

2006-08-15 |
| Bayesian Chi Square TTE fit | This software uses the Bayesian chi square test to evaluate goodness of fit for seven common models for right-censored time-to-event data. |

2006-07-18 |
| CRMSimulator | Toxicity-based dose-finding using the Continual Reassessment Method |

2006-06-21 |
| STATTAB | Double precision statistical tables |

2005-10-30 |
| ToxFinder | Dose-finding in a clinical trial using a combination of two agents |

2005-10-12 |
| bCRM | Bivariate extension of the CRM |

2003-11-20 |
| PerfectMatch | Affymetrix microarray analysis tool |

2003-05-02 |
| MULTINOMPOW | Power of the exact test for a one-sample multinomial distribution |

2003-04-03 |
| TDTASP | Power and sample-size for the TDT and ASP tests |

2003-02-25 |
| CDFLIB90 | Library of routines for cumulative distribution functions, their inverses, and other parameters |

2003-02-24 |
| ONESAMPLE | Confidence interval and tests for one-sample binomial and Poisson |

2003-02-06 |
| ACCFLF | Accelerated failure time model with log-F distribution |

2003-01-28 |
| KSBIN2 | K-stage two-sample binomial |

2003-01-17 |
| KSBIN1 | K-stage binomial, one sample |

2003-01-15 |
| SPPCR | Allele frequency estimation from small-pool PCR data |

2002-09-27 |
| RANDLIB | Library of routines for random number generation |

2002-09-10 |
| EXPSURV | Exploratory survival |

2002-08-23 |
| RANLIST | Randomization lists |

2002-03-19 |
| AOCURR | Analysis of covariance, comparison of slopes and intercepts |

2002-03-19 |
| DRDIST | Calculates statistical tables |

2002-03-19 |
| EVENTCHART | Event chart for time-to-event data |

2002-03-19 |
| GOFCHI | Calculates the chi-square goodness-of-fit test to a set of frequencies |

2002-03-19 |
| INTEGRATE | Numeric integration code for S-PLUS. |

2002-03-19 |
| INVMF | Routine to numerically invert a monotone function |

2002-03-19 |
| KWRANGE | Calculates a multiple range test for a Kruskal-Wallis one-way analysis of variance by ranks |

2002-03-19 |
| P1WAY | Calculates a one-way analysis of variance from means and SDs supplied by the user |

2002-03-19 |
| P2WAY | Calculates a two-way analysis of variance from means and SDs supplied by the user |

2002-03-19 |
| RANGE2 | Calculates a multiple range test for a one-way analysis of variance |

2002-03-19 |
| STUKEL | Stukel's generalizations of the logistic link function |

2002-03-19 |
| TRAX | Transformation of axes |

2001-07-23 |
| SORTF90 | Sort contained FORTRAN 90/95 routines in alphabetic order |

2001-04-30 |
| CUMINC | Cumulative incidence analysis |

1999-06-04 |
| CUMNOR | Cumulative normal (Gaussian) distribution for extreme arguments |

1999-03-02 |
| MUHAZ | Nonparametric Hazard Estimation |

1999-02-19 |
| CRM | Continual Reassessment Method (CRM) for dose-finding in phase I clinical trials |

1998-09-23 |
| BPHASEII | Bayesian boundaries for phase II monitoring |

1997-12-05 |
| BLIP | One-dimensional distribution plots |

1997-11-25 |
| SOGS | Simulation of genotype selection |

1997-10-14 |
| BERDS | Backward elimination via repeated data splitting |

1997-09-02 |
| ASYPOW | Computes asymptotic power or sample size for nonlinear models |

1997-08-12 |
| SINGLE | Single-stage designs for logistic regression when parameter values are uncertain |

1996-04-03 |
| MULTI | Corrections for multiple hypothesis tests |

1995-10-23 |
| FLECS90 | Fortran language extended control structures to FORTRAN 90 |

1995-03-23 |
| CID2BP | Confidence intervals on the difference between two probabilities |

1994-02-10 |
| KSB1CI | k-stage binomial one-group confidence intervals |

1992-03-19 |
| CTA | Contingency table analysis |

1991-03-22 |
| WINDOWS | Windowed estimate code in FORTRAN and S-PLUS |

1991-03-19 |
| SURVAN | Survival analysis |