Last Modified Date | Product Name | Brief Description | |

2018-04-06 |
| Bayesian Optimal Phase 2 (BOP2) Design | A flexible Bayesian optimal design for phase II trials with a single binary, co-primary, nested or bivariate binary endpoints. |

2018-03-15 |
| Sample Size Calculation - Continuous Endpoint | Shiny app provides a free, online, easy-to-use sample size calculator for normal data. Includes the sample size calculation for one, two or more groups. |

2018-02-02 |
| A Phase I/II Design to Identify Optimal Biological Dose for Molecularly Targeted Agents | This design is used to find the optimal biological dose (OBD) for molecularly targeted agents and immunotherapy agents, considering both toxicity and efficacy. The OBD is defined as the dose that is safe and has the highest efficacy. |

2018-01-04 |
| Simon's Two-Stage Design | The Simon's two stage design is a commonly used phase II design. It controls type 1 and type 2 errors, and is optimal in the sense that the expected (or maximum) sample size is minimized if the regimen has low activity (i.e., under the null hypothesis). |

2017-08-31 |
| Bayesian Efficacy Monitoring with Posterior Probability | Bayesian efficacy monitoring with options of early futility and/or efficacy stopping using posterior probability. |

2017-08-31 |
| Bayesian Efficacy Monitoring with Predictive Probability | Bayesian efficacy monitoring with options of early futility and/or efficacy stopping using predictive probability. |

2017-08-31 |
| Bayesian Hierarchical Model - Binomial Data | An interactive application for Bayesian Hierarchical Model - Binomial Data. |

2017-08-31 |
| Bayesian Hierarchical Model - Normal Data | An interactive application for Bayesian Hierarchical Model - Normal Data. |

2017-08-31 |
| Bayesian Toxicity Monitoring | Bayesian toxicity monitoring for evaluating drug safety. |

2017-08-31 |
| Bayesian Update for a Beta-Binomial Distribution | An interactive application to show the Bayesian update of a beta-binomial distribution. |

2017-08-31 |
| Bayesian Update for a Normal Distribution with Known and Unknown Variance | An interactive application to show the Bayesian update of a normal distribution. |

2017-08-31 |
| Bayesian Update for Two Beta-Binomial Distributions | An interactive application to show the Bayesian update of two beta-binomial distributions. |

2017-08-31 |
| Parameter Estimation for A Diagnostic Test | An interactive application to calculate the post-test disease probability given the disease prevalence, sensitivity and specificity of a diagnostic test. |

2017-08-31 |
| Varying Cut-Point and Parameter Estimation of the ROC Curve Analysis | An interactive application to calculate the post-test disease probability given the disease prevalence, marker distributions in the disease group and no-disease group by varying the cut-off point of the marker. |

2017-05-18 |
| Screening for New Onset Diabetes | A web based application for screening for new onset diabetes for CPDPC16-01 |

2016-08-15 |
| Toxicity Severity Weight Visualizer | Shiny app used to visualized the design of severity weights by physicians for different kinds of toxicities |

** DISCLAIMER:**
Unless otherwise stated on a subsequent application-specific web page, these programs are for research purposes only.
We provide absolutely no warranty of any kind, either expressed or implied, including but not limited to the implied warranties of merchantability and fitness for a particular purpose. The entire risk as to the quality and performance of these programs is with the user. Should any of these programs prove defective, the user assumes the cost of all necessary servicing, repair, or correction.
In no event shall The University of Texas or any of its component institutions, including MD Anderson Cancer Center, be liable for damages, including any lost profits, lost monies, or other special, incidental or consequential damages arising out of the use of or inability to use these programs (including but not limited to loss of data or its analysis being rendered inaccurate or losses sustained by third parties).