Upload the previously saved input (a .csv file)
Stop trial if the number of patients assigned to single dose reaches \(n_{stop}\) and the decision is to stay, where \(n_{stop}\) =
Close a dose for backfilling if the number of patients assigned to the dose reaches \(n_{cap}\), where \(n_{cap}\) =
End the backfilling once the dose escalation ends
Eliminate dose \(j\) if\(\ Pr\) (\(p_{_j}\)> \(\phi\) | \(data\)) > \(p_{_E}\)
Check to ensure \( \hat p_{_{MTD}} \leq \) de-escalation boundary, where \(\hat p_{_{MTD}}\) is the isotonic estimate of the DLT probability for the dose selected as the MTD.
Please upload simulation toxicity and response scenarios file with the template: csv file template
Check the box to confirm that design parameters have been entered under Trial Setting.