U2OET

Phase I/II dose-pair-finding based on utilities of 3-level ordinal efficacy and toxicity

This is a menu-driven computer program for implementing the dose-finding method described in detail in the paper “Utility-Based Optimization of Combination Therapy Using Ordinal Toxicity and Efficacy in Phase I/II Trials” by Houede, Thall, Nguyen, Paoletti, and Kramar (2009).

Please read this paper carefully before using this computer program.

A preprint of the paper may be obtained by contacting Peter Thall.

This computer program was written by Hoang Nguyen using Visual C++.