Toxicity Probability Intervals

Software for implementing the method described in "Dose-finding in oncology clinical trials based on toxicity probability intervals" by Yuan Ji, Yisheng Li, and Nebiyou Bekele. This software uses Microsoft Excel to produce a table that can be used to conduct the trial. Simulation software, written in R, is also provided.

Please note that to run the software as an Excel macro, your macro security must be set to "Medium" or "Low". To do this, open Excel, click on Tools, select Macro from the drop-down list, and click Security. Set the security level to "Medium" or "Low" in the pop-up window by clicking the button in front of the desired level. Once you have selected your desired security level, click OK and close Excel. You are now ready to open this macro. Once the macro is opened, a smiley-face icon will appear in the toolbar. Clicking on the icon will run this macro. If your security level is already set to "Medium" or "Low", the smiley-face icon will appear automatically.

Software developed by Yuan Ji and Richard Herrick.